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Nagamine, Takeaki*; Takada, Hisashi*; Kusakabe, Takahiko*; Nakazato, Kyomi*; Sakai, Takuro; Oikawa, Masakazu*; Kamiya, Tomihiro; Arakawa, Kazuo; Iha, Masahiko*
Biological Trace Element Research, 124(1), p.60 - 69, 2008/07
Times Cited Count：2 Percentile：6.91(Biochemistry & Molecular Biology)This study was undertaken to elucidate the intracellular changes of metal elements after the administration of fucoidan extracted from . TRL1215 cells (normal rat liver cell line) were treated with 0, 0.1, or 1.0 mg/mL fucoidan. The cellular distribution of elements was analyzed using in-air micro-PIXE induced X-ray emission. In fucoidan-treated cells, the focal accumulation of Br (BrdU) was correlated spatially with phosphorous-rich region, suggesting that Br was localized within the nucleus. Al distribution provided a spatial association with Br map. These data suggest that fucoidan binding Al us postulated to be transferred into the nucleus.
Ozaki, Takuo; Ambe, Shizuko*; Abe, Tomoko*; Francis, A. J.
Biological Trace Element Research, 90(1-3), p.273 - 281, 2002/12
Times Cited Count：4 Percentile：6.56(Biochemistry & Molecular Biology)no abstracts in English
-ray analysis using cold and thermal guided neutron beams at JAERIYonezawa, Chushiro
Biological Trace Element Research, 71-72, p.407 - 413, 1999/00
Times Cited Count：7 Percentile：15.12(Biochemistry & Molecular Biology)no abstracts in English
